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Exor n.v.
Nantahala Capital Management, LLC
Deerfield Management Company, l.p.
Perceptive Advisors LLC
Kingdon Capital Management, l.l.c.
Affinity Asset Advisors, LLC
Orbimed Advisors LLC
Ikarian Capital, LLC
Lilly Endowment Inc
Eversept Partners, Lp
Sabby Management, LLC
Baker Bros. Advisors Lp
Braidwell Lp
Kite Lake Capital Management (Uk) LLP
Silverarc Capital Management, LLC
Great Point Partners LLC
Sofinnova Investments, Inc.
Patient Capital Management, LLC
Sphera Funds Management Ltd.
Stonepine Capital Management, LLC
Rbo & Co LLC
Sand Grove Capital Management LLP
Bruce & Co., Inc.
Octagon Capital Advisors Lp
Sio Capital Management, LLC
Fourworld Capital Management LLC
Ally Bridge Group (Ny) LLC
Artia Global Partners Lp
Gagnon Securities LLC
Investor Ab
Whitefort Capital Management, Lp
Rubric Capital Management Lp
Ra Capital Management, l.p.
Yakira Capital Management, Inc.
Rtw Investments, Lp
Avoro Capital Advisors LLC
General American Investors Co Inc
Blue Door Asset Management, LLC
Claret Asset Management Corp
Deep Track Capital, Lp
Gagnon Advisors, LLC
Caligan Partners Lp
Paradigm Biocapital Advisors Lp
Bellevue Group Ag
Duquesne Family Office LLC
Trivant Custom Portfolio Group, LLC
Frazier Life Sciences Management, l.p.
Tcg Crossover Management, LLC
Parkman Healthcare Partners LLC
Puzo Michael J