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Lilly Endowment Inc
Vivo Capital, LLC
Sivik Global Healthcare LLC
Flagship Pioneering Inc.
Tower House Partners LLP
Neumann Capital Management, LLC
Regents of the University of California
Krensavage Asset Management, LLC
Wrapmanager Inc
Sarissa Capital Management Lp
Forefront Analytics, LLC
Lumina Fund Management LLC
Pfm Health Sciences, Lp
Rp Management, LLC
Sector Gamma As
Pura Vida Investments, LLC
Rafferty Asset Management, LLC
Tamarack Advisers, Lp
Avoro Capital Advisors LLC
Bruce & Co., Inc.
Newtyn Management, LLC
Robert Wood Johnson Foundation
Compass Financial Group, Inc.
Rhenman & Partners Asset Management Ab
First Light Asset Management, LLC
Eversept Partners, Lp
Bridger Management, LLC
Healthcor Management, l.p.
Acuta Capital Partners, LLC
Prosight Management, Lp
Suvretta Capital Management, LLC
Tekla Capital Management LLC
Great Point Partners LLC
Palo Alto Investors Lp
Endurant Capital Management Lp
Foresite Capital Management Iii, LLC
Baker Bros. Advisors Lp
New Vernon Capital Holdings Ii LLC
Rubric Capital Management Lp
Sphera Funds Management Ltd.
Bellevue Group Ag
Knoll Capital Management, LLC
Mcadam, LLC
Paragon Wealth Strategies, LLC
Orbimed Advisors LLC
Finepoint Capital Lp
International Biotechnology Trust Plc
Athanor Capital, Lp
Armistice Capital, LLC
Ghost Tree Capital, LLC
Sio Capital Management, LLC
Frazier Management LLC
Interwest Venture Management Co
Davide Leone & Partners Investment Co Ltd.
Sabby Management, LLC
Highvista Strategies LLC
Dafna Capital Management LLC
Rainey & Randall Investment Management Inc.
Marshall Financial Group Inc /adv
Summit Rock Advisors, Lp
Oracle Investment Management Inc
Sofinnova Investments, Inc.
Northwestern University
New Leaf Venture Partners, l.l.c.
Sectoral Asset Management Inc
Wilshire Advisors LLC
Stonepine Capital Management, LLC
Rock Springs Capital Management Lp
Ecor1 Capital, LLC
Bvf Inc/il
Rtw Investments, Lp
Starr International Co Inc
Boxer Capital, LLC
Summer Road LLC
Consonance Capital Management Lp
Spinnaker Capital LLC
Meditor Group Ltd
Aquilo Capital Management, LLC
Birchview Capital, Lp
Aviva Holdings Ltd.
Opaleye Management Inc.
Foresite Capital Management Iv, LLC
Cpmg Inc
Trv Gp Ii, LLC
Monashee Investment Management LLC
Cormorant Asset Management, Lp
Venbio Partners LLC
Harvard Management Co Inc
Bain Capital Life Sciences Investors, LLC
Third Security, LLC
Caxton Corp
Aisling Capital Management Lp
Perceptive Advisors LLC
Redmile Group, LLC
Versant Venture Management, LLC
Artal Group s.a.
Sv Health Investors, LLC
Novo Holdings A/s
Casdin Capital, LLC
Omega Fund Management, LLC